PacificDx Clinical Laboratory

Our fully accredited and licensed clinical laboratory, PacificDx, is a wholly-owned subsidiary of ResearchDx. As a premier CLIA (Clinical Laboratory Improvement Act), CAP (College of American Pathologists) and ISO (International Organization for Standardization) laboratory, our collaborative reputation is solidly built on our client’s successes.

Learn more about our clinical laboratory compliance or Private Health Information policy.

Laboratory Capabilities

Supported by experienced scientists and project managers, PacificDx has extensive experience in various technologies, platforms and in-depth understanding of the entire diagnostics pathway from discovery through final commercial product. Our laboratory provides analytical, clinical, esoteric and consulting laboratory services to pharmaceutical, biotechnology and diagnostics companies. Learn more about our list of services here.

Genomics Technologies

We support diverse sequencing and genomic technologies for use in IVD development in the fields of oncology, infectious diseases and heritable diseases.

  • Illumina® MiSeq, MiSeqDx & NextSeq 500
  • Ion Torrent PGM™
  • Qiagen GeneReader
  • Exome, Transcriptome, cfDNA, single-cell RNA/DNA Seq, Single-cell lowpass
  • Oncology and Custom panels

  • Qiagen Rotor-Gene® Q MDx
  • Applied Biosystems 7900HT
  • Applied Biosystems® QuantStudio®6
  • Commercial and custom assays

  • Agilent Microarray scanner (G2600D)
  • Affymetrix GeneChip®
  • CNV, SNP, Methylation, Expression

  • All commercially available probes
  • Custom probe design and manufacture
  • RUO, IUO and GMP manufacture

Cell & Tissue Methodologies

We support anatomic pathology, liquid cell sorting and enrichment, and cytogenetics techniques deployed for various applications, particularly oncology.

  • Beckman Coulter FC500
  • Commercial and custom flow panel for hematology and lymphoid malignancies
  • Biomarker detection

  • Fluorescence Activated Cell Sorting (FACS)
  • Sillicon Bio DEPArray™, DEPArray™NxT
  • Individual tumor and stromal cell recovery from FFPE and CTC samples

  • Metasystems Metafer imaging station
  • Carl Zeiss Auto Imager
  • IHC, H&E on FFPE and Frozen tissue
  • Pathology review and macro-dissection

  • 100+ characterized control cell lines for oncology applications
  • FFPE control cell block preparation
  • Control DNA/RNA preparation

Support Technologies

We support diverse technologies for IVD development and scale-up activities that may require automated DNA extraction and liquid-handling systems.

  • Direct and Sandwich ELISA
  • Identify and qualify commercial fit for purpose ELISA kits for PK & PD studies
  • Wide applicability for assay development
  • Analyte detection e.g., cytokines

  • Tecan GENios Pro®
  • Dynex® MRX

  • Hamilton Star, Microlab Star
  • QIACube®
  • QIASymphony® SP
  • Scale-up applications